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Analyzing Longitudinal Clinical Trial Data: A Practical by Craig Mallinckrodt,Ilya Lipkovich

By Craig Mallinckrodt,Ilya Lipkovich

Analyzing Longitudinal medical Trial info: a pragmatic consultant offer useful and simple to enforce ways for bringing the most recent conception on research of longitudinal medical trial information into regimen practice.?This ebook, with its example-oriented process that incorporates a number of SAS and R code fragments, is a vital source for statisticians and graduate scholars focusing on clinical study.

The authors supply transparent descriptions of the suitable statistical conception and illustrate sensible concerns for modeling longitudinal facts. themes coated comprise selection of endpoint and statistical try out; modeling capability and the correlations among repeated measurements; accounting for covariates; modeling specific information; version verification; tools for incomplete (missing) info that comes with the newest advancements in sensitivity analyses, besides ways for and matters in deciding on estimands; and skill for fighting lacking info. each one bankruptcy stands on my own in its insurance of a subject matter. The concluding chapters supply particular recommendation on find out how to combine those self sufficient themes into an over-arching learn improvement approach and statistical research plan.

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